Abstract: This paper analyzes the trend of winter tourism climate comfort in Guangxi and the scenario prediction for 2024-2080 based on the observational data of Guangxi National Meteorological Stations from 1971-2023 and the RegCM4.4 Regional Climate Model prediction data. The study shows that the number of winter climate comfort days in most areas of Guangxi from 1971 to 2023 is in the range of 60-86 d, accounting for more than two thirds of the total winter, with relatively few days of heat discomfort and cold discomfort. In particular, the area west of 108°E is the most comfortable region for winter climate. The winter temperature in Guangxi shows a significant increasing trend, resulting in an increase in the number of comfortable days and a decrease in the number of cold-uncomfortable days, which is especially significant for the eastern and northwestern mountainous regions in terms of tourism climate comfort. The results of future projections show that the overall winter tourism climate comfort in Guangxi will increase significantly during the period of 2024-2080, with an increasing trend of 1.2 d/10 a and 0.7 d/10 a in the number of comfortable days under the RCP4.5 and RCP8.5 scenarios, respectively, and with the largest increment in the 21st century 60s. Spatial differences were obvious, with an overall trend of increasing comfortable days in the north and decreasing in the south, an overall decrease in cold uncomfortable days, and a significant increase in heat uncomfortable days (RCP8.5). Controlling greenhouse gas emissions is essential to maintain winter tourism comfort in Guangxi, especially in the southern region. The results of the study provide a decision-making basis for climate adaptation and ecological regulation for the sustainable development of winter tourism in Guangxi.